In this section of GMP-inspection.com, our translators provide definitions and explanations of various specialized terms from the pharmaceutical industry and GMP (Good Manufacturing Practice).
Ointments are semi-solid dosage forms that are usually applied to the skin or mucous membranes for topical treatment. Ointments (German translation: Salben) can have different textures, from pasty to creamy, and they are intended for different purposes. They can be nourishing or protective. If ointments contain an active pharmaceutical ingredient, they can also be used to treat skin diseases or relieve pain, for example. In contrast to creams (translation into German: Cremes), ointments consist of a single-phase, homogeneous base that is usually lipophilic but can also be hydrophilic (i.e. water-absorbent).
Here are some types of ointments and their uses:
Like other semi-solid dosage forms (German: halbfeste Arzneiformen), ointments are usually applied directly to the area to be treated and, depending on their composition, are either absorbed or remain on the surface of the skin. They can be used alone or in combination with other drugs such as tablets or injections, depending on the type and location of the disease.
The use of ointments is also based on the doctor’s instructions and the information on the packaging of the medication.
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